About 6 results found for searched term "HCN Channel" (0.134 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M5079 | Zatebradine hydrochloride | HCN Channel |
| UL-FS-49 | ||
| Zatebradine(UL-FS49) is a highly effective HCN ion channel antagonist, which can reversively reduce heart rate and inhibit hHCN1 up to 92% at 10uM concentration. | ||
| M6063 | Zatebradine | HCN Channel |
| UL-FS49 | ||
| Zatebradine(UL-FS49) is a potent HCN channels antagonist, which decreased the heartbeat in a reversible manner; 92% inhibition of the hHCN1-mediated current at 10 uM. | ||
| M7768 | DK-AH 269 | HCN Channel |
| DK-AH 269 (Cilobradine) is an HCN Channel blocker; an open channel blocker of neuronal Ih and related cardiac If channels. | ||
| M7877 | KT 5720 | PKA |
| KT 5720 is a specific, reversible, ATP-competitive, cell-permeable protein kinase A (PKA) inhibitor with an IC50 value of 3.3 μM, which effectively reverses MDR1-mediated multidrug resistance and reduces excitability of dorsal root ganglion (DRG) neurons by attenuating the activity of hyperpolarization-activated cyclic nucleotide-gated cation (HCN) channels and decreasing the intracellular Ca2+ concentration. ) neurons by reducing hyperpolarization-activated cyclic nucleotide-gated cation (HCN) channel activity and intracellular Ca2+ concentration. It can be used in the study of hematologic malignancies and diseases associated with HCN and DRG neurons. | ||
| M14225 | ZD7288 | HCN Channel |
| ICI D7288 | ||
| ZD7288 (ICI D7288) is a selective hyperpolarization-activated cyclic nucleotide-gated (HCN) channel blocker. | ||
| M45262 | KIO-301 | HCN Channel |
| KIO-301 a photoswitchable HCN channel blocker, and dihydroorotic acid ester dehydrogenase (DHODH) inhibitor for studies related to ocular diseases. | ||
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